Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 5/20 | 0.40 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17469729 | 0.81 | TMPRSS2 (0.51) | GRM5ASIC3ERN1PDGFRBKDR | |
| SCHEMBL7346923 | 0.74 | ASIC3 (0.68) | GRM5ASIC3ERN1PLAU | |
| SCHEMBL25280998 | 0.74 | PDGFRB (0.55) | GRM5PDGFRBKDRIKBKB | |
| SCHEMBL30563484 | 0.74 | PDGFRB (0.55) | GRM5PDGFRBKDRIKBKB | |
| SCHEMBL25841112 | 0.72 | GRM5 (0.49) | GRM5ERN1 | |
| SCHEMBL25845879 | 0.71 | PDGFRB (0.57) | GRM5PDGFRBKDRIKBKB | |
| SCHEMBL25231590 | 0.70 | KDR (0.59) | GRM5PDGFRBKDR | |
| SCHEMBL25231184 | 0.70 | PDGFRB (0.56) | GRM5TACR2TACR1PDGFRBKDR | |
| SCHEMBL25244359 | 0.70 | PDGFRB (0.61) | GRM5PDGFRBKDRHAO1 | |
| SCHEMBL25232365 | 0.70 | GRM5 (0.68) | GRM5TACR2TACR1PDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016014674-A1 | LINKED DIARYL COMPOUNDS WITH ANTICANCER PROPERTIES AND METHODS OF USING THE SAME | UNIVERSITY OF MARYLAND, COLLEGE PARK (US) | 2016-01-28 | — | — | WO | disclosed |