Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | GSTO1 | P78417 | 5/20 | 0.49 |
| ▸ | CPB1 | P15086 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.43 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746506 | 0.82 | KMT2A (0.57) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL4261629 | 0.82 | KMT2A (0.55) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL4261635 | 0.82 | KMT2A (0.55) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL1746621 | 0.80 | KMT2A (0.60) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL18674599 | 0.79 | KMT2A (0.64) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL1747118 | 0.79 | KMT2A (0.52) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL1746662 | 0.78 | KMT2A (0.57) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL1747124 | 0.78 | KMT2A (0.58) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL1745189 | 0.77 | GSTO1 (0.54) | KMT2AMEN1L3MBTL1GSTO1CPB1 | |
| SCHEMBL1747338 | 0.76 | KMT2A (0.56) | KMT2AMEN1L3MBTL1GSTO1CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |
| US-7960369-B2 | Receptor function regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-06-14 | — | — | US | disclosed |