Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8144288 | 0.90 | MAPT (0.51) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL8152290 | 0.85 | MAPT (0.48) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL3543571 | 0.84 | ALDH1A1 (0.46) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL31009356 | 0.84 | MAPT (0.49) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL15794676 | 0.84 | ALDH1A1 (0.62) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL24168437 | 0.83 | MAPT (0.54) | MAPTMEN1KMT2ALMNAKIF11 | |
| SCHEMBL8143585 | 0.83 | MAPT (0.50) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL30539127 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL5224826 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2AHTTLMNA | |
| SCHEMBL14678190 | 0.80 | MAPT (0.51) | MAPTMEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980072-A1 | PHENYL DERIVATIVE | ONO Pharmaceutical Co., Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |