SCHEMBL174734

SCHEMBL174734

C=CC(=O)NC(C)(C)C(C)C

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.48
PIK3CD O00329 1/20 0.45
ALDH1A1 P00352 3/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
MAPK1 P28482 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TGM2 P21980 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21439808 0.84 TSHR (0.46) TSHRPIK3CDALDH1A1CYP3A4CYP2C9
SCHEMBL137801 0.83 TSHR (0.45) TSHRPIK3CDALDH1A1CYP3A4CYP2C9
Hydrochloric Acid SCHEMBL9234605 0.81 TSHR (0.43) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL1140485 0.81 TSHR (0.43) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL25563795 0.81 TSHR (0.43) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL9572182 0.79 TSHR (0.42) TSHRALDH1A1CYP3A4CYP2C9CYP2C19
SCHEMBL21728873 0.79 TSHR (0.42) TSHRPIK3CDALDH1A1CYP3A4CYP2C9
SCHEMBL8435733 0.79 PIK3CD (0.47) TSHRPIK3CDPOLB
SCHEMBL19168937 0.78 TSHR (0.45) TSHRPIK3CDALDH1A1CYP3A4CYP2C9
SCHEMBL7703896 0.78 TSHR (0.45) TSHRPIK3CDALDH1A1CYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119060659-A Adhesive composition, adhesive film, antistatic surface protective film for polarizing plate, and adhesive-equipped optical film 藤森工业株式会社 2024-12-03 CN claimed
EP-0611566-B1 Aqueous aerosol lacque for fixing hair OREAL (FR) 1997-05-07 EP claimed
US-5587145-A COPOLYMER CONTAINING UNSATURATED SULFONIC ACID WITH SPECIFIC DEGREE OF NEUTRALIZATION AND N-MONOALKYL(METH)ACRYLAMIDE, DIMETHYL ETHER PROPELLANT L'OREAL (FR) 1996-12-24 US claimed
EP-0611566-A1 Aqueous aerosol lacque for fixing hair L'OREAL (FR) 1994-08-24 EP claimed
CN-119060659-A Adhesive composition, adhesive film, antistatic surface protective film for polarizing plate, and adhesive-equipped optical film 藤森工业株式会社 2024-12-03 CN disclosed
US-11332455-B2 α,β-unsaturated amide compound KYOWA KIRIN CO., LTD. (JP) 2022-05-17 US disclosed
US-20210380551-A1 ALPHA,BETA-UNSATURATED AMIDE COMPOUND KYOWA KIRIN CO., LTD. (JP) 2021-12-09 US disclosed
CN-113646396-A Aqueous coating composition 湛新荷兰 2021-11-12 CN disclosed
EP-2795406-B1 ALCOHOL-SOLUBLE HOLE TRANSPORT MATERIALS FOR ORGANIC PHOTOCONDUCTOR COATINGS HEWLETT PACKARD DEVELOPMENT CO LP (US) 2017-02-08 EP disclosed
US-9482970-B2 Organic photoconductors having protective coatings with nanoparticles HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2016-11-01 US disclosed
EP-2831674-B1 ORGANIC PHOTOCONDUCTORS HAVING PROTECTIVE COATINGS WITH NANOPARTICLES HEWLETT PACKARD DEVELOPMENT CO (US) 2016-03-30 EP disclosed
EP-2488300-B1 PROCESS FOR PRODUCING POSITIVELY CHARGED POLYMER ENCAPSULATED PARTICLES HEWLETT PACKARD DEVELOPMENT CO (US) 2016-02-24 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
EP-0611566-A1 Aqueous aerosol lacque for fixing hair L'OREAL (FR) 1994-08-24 EP disclosed
US-5275811-A Terpolymer resin of vinyl ester, acrylamide and maleate ISP INVESTMENTS INC. (US) 1994-01-04 US disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
US-5196495-A Hair spray; terpolymer of a vinyl ester, alkyl maleate half ester and a substituted acrylamide ISP INVESTMENTS INC. (US) 1993-03-23 US disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
WO-1992013014-A1 HAIR FIXATIVE POLYMERS ISP INVESTMENTS INC. (US) 1992-08-06 WO disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210380551-A1 ALPHA,BETA-UNSATURATED AMIDE COMPOUND NR1H2, NR1H3, NCOA1 TSHR 1080/4885PIK3CD 4029/4885ALDH1A1 754/4885
US-11332455-B2 α,β-unsaturated amide compound NR1H2, NCOA1, NR0B1 TSHR 791/4885PIK3CD 4283/4885ALDH1A1 816/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.