Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3315750 | 0.82 | ALDH1A1 (0.43) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL174734 | 0.78 | TSHR (0.48) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL421304 | 0.78 | — | — | |
| SCHEMBL27685216 | 0.77 | ALDH1A1 (0.40) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19168937 | 0.75 | TSHR (0.45) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL902120 | 0.75 | PIK3CD (0.35) | PIK3CD | |
| Hydrochloric Acid SCHEMBL5161593 | 0.75 | TSHR (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL29192600 | 0.75 | TSHR (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28364763 | 0.74 | TSHR (0.48) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6572407 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1147138-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | The B.F. Goodrich Company (US) | 2001-10-24 | — | — | EP | claimed |
| WO-2000039176-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | THE B.F. GOODRICH COMPANY (US) | 2000-07-06 | — | — | WO | claimed |
| US-6361768-B1 | POLYMER FORMED BY COPOLYMERIZATION OF ANIONIC MONOMER HAVING CARBOXY-FUNCTIONAL GROUP, NON-QUATERNIZED CATIONIC MONOMER HAVING AMINO-FUNCTIONAL GROUP, NON-IONIC HYDROPHILIC MONOMER, HYDROPHOBIC MONOMER, OPTIONAL CROSSLINKING MONOMER | PMD HOLDINGS CORP. | 2002-03-26 | — | — | US | disclosed |
| EP-1147138-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | The B.F. Goodrich Company (US) | 2001-10-24 | — | — | EP | disclosed |
| WO-2000039176-A1 | HYDROPHILIC AMPHOLYTIC POLYMER | THE B.F. GOODRICH COMPANY (US) | 2000-07-06 | — | — | WO | disclosed |
| US-5141717-A | Carbon monitor containing anion exchange resin | IONICS, INCORPORATED (US) | 1992-08-25 | — | — | US | disclosed |