⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468442 | 0.77 | — | — | |
| SCHEMBL1118434 | 0.73 | — | — | |
| SCHEMBL1118432 | 0.73 | — | — | |
| SCHEMBL23989909 | 0.73 | — | — | |
| SCHEMBL246940 | 0.69 | — | — | |
| SCHEMBL12269595 | 0.69 | ALDH1A1 (0.31) | — | |
| SCHEMBL15088577 | 0.69 | — | — | |
| SCHEMBL1118561 | 0.69 | — | — | |
| SCHEMBL1377751 | 0.69 | — | — | |
| SCHEMBL74184 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4747234-A1 | KV1.3 POTASSIUM CHANNEL ANTAGONISTS | Muna Therapeutics ApS (DK) | 2026-05-27 | — | — | EP | claimed |
| WO-2025017103-A1 | KV1.3 POTASSIUM CHANNEL ANTAGONISTS | MUNA THERAPEUTICS APS (DK) | 2025-01-23 | — | — | WO | claimed |
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |
| US-10975095-B2 | — | — | 2021-04-13 | — | — | US | disclosed |
| EP-3652178-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | H. Hoffnabb-La Roche Ag (CH) | 2020-05-20 | — | — | EP | disclosed |
| CN-110191880-A | Isoxazolidin-5-one derivative and herbicide containing the same as active ingredient | 北兴化学工业株式会社 | 2019-08-30 | — | — | CN | disclosed |
| US-20190100530-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | GENENTECH, INC. (US) | 2019-04-04 | — | — | US | disclosed |
| WO-2019012063-A1 | BICYCLIC KETONE COMPOUNDS AND METHODS OF USE THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2019-01-17 | — | — | WO | disclosed |
| US-10035889-B2 | Optical film | MITSUI CHEMICALS, INC. (JP) | 2018-07-31 | — | — | US | disclosed |
| US-20160032063-A1 | Optical Film | KEIO UNIVERSITY (JP) | 2016-02-04 | — | — | US | disclosed |
| CN-102906150-B | Optical material and molded article thereof | MITSU CHEMICALS INC | 2014-11-19 | — | — | CN | disclosed |
| CN-102906150-A | Optical material and molded article thereof | MITSUI CHEMICALS INC | 2013-01-30 | — | — | CN | disclosed |
| CN-101437827-B | Process for producing optically active chromene oxide compound | NISSAN CHEMICAL IND LTD | 2012-08-29 | — | — | CN | disclosed |
| CN-101636392-A | Process for production of optically active epoxy compound | NISSAN CHEMICAL IND LTD | 2010-01-27 | — | — | CN | disclosed |
| CN-101437827-A | Process for producing optically active chromene oxide compound | NISSAN CHEMICAL IND LTD (JP) | 2009-05-20 | — | — | CN | disclosed |