Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.44 |
| ▸ | PRCP | P42785 | 6/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747635 | 0.98 | KCNH2 (0.49) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL691517 | 0.91 | CYP3A4 (0.56) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL15673803 | 0.90 | CYP3A4 (0.59) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL18171455 | 0.89 | CYP3A4 (0.63) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL3350505 | 0.87 | CYP3A4 (0.55) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12175001 | 0.86 | CYP3A4 (0.62) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL1747524 | 0.85 | KCNH2 (0.52) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL3341874 | 0.85 | CYP3A4 (0.59) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL12175233 | 0.84 | KCNH2 (0.63) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 | |
| SCHEMBL1747585 | 0.84 | KCNH2 (0.56) | KCNH2CYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385048-A1 | Hepatitis C virus inhibitors | Bristol-Myers Squibb Company (US) | 2011-11-09 | — | — | EP | disclosed |
| US-20110268697-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2011-11-03 | — | — | US | disclosed |
| US-20110252687-A1 | Canting Vertical Fore Grip with Bipod | GRIP POD SYSTEMS, LLC | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110268697-A1 | Hepatitis C Virus Inhibitors | HAVCR2, PYGL, HCCS | KCNH2 4523/4885CYP3A4 1107/4885CYP2C9 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.