SCHEMBL174757

SCHEMBL174757

Nc1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.46
MAPK1 P28482 2/20 0.46
TSHR P16473 6/20 0.43
TP53 P04637 1/20 0.43
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
MEN1 O00255 1/20 0.42
NPC1 O15118 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
APEX1 P27695 1/20 0.42
RECQL P46063 1/20 0.42
RAB9A P51151 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
MCL1 Q07820 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GAA P10253 1/20 0.40
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8714149 0.97 CYP3A4 (0.46) CYP3A4MAPK1TSHRTP53ALDH1A1
Ethylene SCHEMBL15522510 0.94 CYP3A4 (0.42) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL526351 0.87 ALDH1A1 (0.50) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL11690344 0.83 CYP3A4 (0.50) CYP3A4MAPK1TSHRTP53ALDH1A1
Trichloroacetic Acid SCHEMBL11439310 0.80 ALDH1A1 (0.40) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL348089 0.79 CYP3A4 (0.62) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL29368277 0.79 CYP3A4 (0.62) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL1493725 0.79 CYP3A4 (0.42) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL29674897 0.79 CYP3A4 (0.42) CYP3A4MAPK1TSHRTP53ALDH1A1
SCHEMBL1813012 0.79 TSHR (0.42) CYP3A4MAPK1TSHRTP53ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 780 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798252-A Method for preparing N-ortho-acyl substituted nitrogen-containing heterocyclic compound and amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2025-04-11 CN claimed
CN-114113370-B Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2024-03-26 CN claimed
CN-109970588-B Nontoxic durable antifouling paint and preparation method thereof 武汉南望环保技术研究有限责任公司 2024-03-08 CN claimed
CN-113845612-B Preparation method of main catalyst, catalyst and application thereof 中国石油天然气股份有限公司 2023-02-28 CN claimed
CN-113307972-B Polyimide and preparation method thereof, and polyimide sealing ring and preparation method thereof 中国科学院长春应用化学研究所 2022-06-07 CN claimed
CN-114113370-A Analysis method of aromatic halogenated disinfection byproducts in water 东南大学 2022-03-01 CN claimed
CN-113845612-A Preparation method of main catalyst, catalyst and application thereof 中国石油天然气股份有限公司 2021-12-28 CN claimed
CN-113307972-A Polyimide and preparation method thereof, and polyimide sealing ring and preparation method thereof 中国科学院长春应用化学研究所 2021-08-27 CN claimed
CN-108786176-B Method for liquid-liquid microextraction of fungomycin in fruit juice by aid of acid-assisted dispersion liquid 华南农业大学 2020-11-03 CN claimed
CN-108341416-B Needle-shaped nano zeolite material prepared from metakaolin as well as method and application thereof 浙江工业大学 2020-10-09 CN claimed
WO-1996018625-A1 METHOD FOR OBTAINING A NOVEL RANGE OF SYNTHETIC PREPARATIONS FOR PHYTOSANITARY USE KERSERHO FRANCOIS MARIE (FR) 1996-06-20 WO claimed
CN-1026980-C Synthesis process of alpha-ethoxyformyl-beta- (polyhalogenated anilino) -ethyl acrylate NANJING PHARMACEUTIC INST (CN) 1994-12-14 CN claimed
EP-0319452-B1 Monoazo pigments, process to manufacture them and their use HOECHST AG (DE) 1994-05-18 EP claimed
US-5086168-A MONOAZO PIGMENTS DERIVED FROM DIAZOTIZED DI- OR TRICHLOROANILINES, PREPARATION THEREOF AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1992-02-04 US claimed
CN-1057830-A α-ethoxycarbonyl-β-(phenyl polyhalide amido)-ethyl propenoate synthesis technique MEDICAL INST NANJING CITY (CN) 1992-01-15 CN claimed
EP-0319452-A2 Monoazo pigments, process to manufacture them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1989-06-07 EP claimed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 US claimed
US-4085141-A Process for the preparation of anilines meta-substituted by chlorine BAYER AKTIENGESELLSCHAFT (DT) 1978-04-18 US claimed
US-4009228-A TACKIFIERS FOR RUBBERS AND THERMOPLASTICS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-02-22 US claimed
US-3989756-A RANEY CATALYST, DEHALOGENATION INHIBITOR NIPPON KAYAKU KABUSHIKI KAISHA (JA) 1976-11-02 US claimed