Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.65 |
| ▸ | TSHR | P16473 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.65 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.65 |
| ▸ | DRD1 | P21728 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.65 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.65 |
| ▸ | DRD3 | P35462 | 1/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.65 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.65 |
| ▸ | EYA2 | O00167 | 1/20 | 0.60 |
| ▸ | APP | P05067 | 1/20 | 0.60 |
| ▸ | ACE | P12821 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicine SCHEMBL34161 | 0.97 | ALOX15 (0.68) | ALOX15TSHRTDP1KDM4EBLM | |
| Bicine SCHEMBL177696 | 0.97 | ALOX15 (0.68) | ALOX15TSHRTDP1KDM4EBLM | |
| Ammonia Solution, Strong SCHEMBL15643061 | 0.95 | ALOX15 (0.75) | ALOX15TSHRTDP1KDM4EBLM | |
| Edetic Acid SCHEMBL9325471 | 0.95 | ALOX15 (0.75) | ALOX15TSHRTDP1KDM4EBLM | |
| Ammonia Solution, Strong SCHEMBL9749925 | 0.95 | ALOX15 (0.75) | ALOX15TSHRTDP1KDM4EBLM | |
| Ammonia Solution, Strong SCHEMBL2281626 | 0.95 | ALOX15 (0.75) | ALOX15TSHRTDP1KDM4EBLM | |
| Bicine SCHEMBL20471950 | 0.94 | ALOX15 (0.65) | ALOX15TSHRTDP1KDM4EBLM | |
| Bicine SCHEMBL5883443 | 0.94 | ALOX15 (0.65) | ALOX15TSHRTDP1KDM4EBLM | |
| Bicine SCHEMBL3357098 | 0.94 | ALOX15 (0.65) | ALOX15TSHRTDP1KDM4EBLM | |
| SCHEMBL8968107 | 0.94 | TDP1 (0.74) | ALOX15TSHRTDP1KDM4EBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1534334-B1 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | BELROSE PHARMA INC (US) | 2014-06-25 | — | — | EP | disclosed |
| EP-2338513-A2 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | ENZON, INC. (US) | 2011-06-29 | — | — | EP | disclosed |
| US-7897647-B2 | Useful in extending the in vivo circulating life of biologically active materials; bicine linker allows for the manipulation of the hydrolysis rate of the prodrug, thereby releasing the native entities at various rates in vivo as well as in vitro | ENZON PHARMACEUTICALS, INC. (US) | 2011-03-01 | — | — | US | disclosed |
| US-7597437-B2 | Ink jet ink composition, ink set and ink jet treatment liquid, and ink jet recording method and ink jet recording apparatus using the same | FUJI XEROX CO., LTD. (JP) | 2009-10-06 | — | — | US | disclosed |
| EP-1534334-A4 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON INC (US) | 2008-04-16 | — | — | EP | disclosed |
| EP-1628687-A4 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON INC (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20070166276-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | ENZON PHARMACEUTICALS, INC. | 2007-07-19 | — | — | US | disclosed |
| US-20070109380-A1 | Ink jet ink composition, ink set and ink jet treatment liquid, and ink jet recording method and ink jet recording apparatus using the same | FUJI XEROX CO., LTD. (JP) | 2007-05-17 | — | — | US | disclosed |
| US-20060286065-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | BELROSE PHARMA INC. | 2006-12-21 | — | — | US | disclosed |
| US-7122189-B2 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | ENZON, INC. (US) | 2006-10-17 | — | — | US | disclosed |
| US-7087229-B2 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | ENZON PHARMACEUTICALS, INC. (US) | 2006-08-08 | — | — | US | disclosed |
| EP-1628687-A2 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON, INC. (US) | 2006-03-01 | — | — | EP | disclosed |
| EP-1534334-A1 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON, INC. (US) | 2005-06-01 | — | — | EP | disclosed |
| US-20050003448-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | BELROSE PHARMA INC. | 2005-01-06 | — | — | US | disclosed |
| WO-2004108070-A2 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| US-20040241348-A1 | Recording paper, and image recording method and device using the same | FUJI XEROX CO., LTD. (JP) | 2004-12-02 | — | — | US | disclosed |
| US-20040207701-A1 | Ink jet ink composition, ink set and ink jet treatment liquid, and ink jet recording method and ink jet recording apparatus using the same | FUJI XEROX CO., LTD. (JP) | 2004-10-21 | — | — | US | disclosed |
| US-20040037802-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | BELROSE PHARMA INC. | 2004-02-26 | — | — | US | disclosed |
| WO-2004014424-A1 | RELEASABLE POLYMERIC CONJUGATES BASED ON ALIPHATIC BIODEGRADABLE LINKERS | ENZON, INC. (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050003448-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | CD44, PAICS, PCBP1 | ALOX15 1113/4885TSHR 4144/4885TDP1 1229/4885 |
| US-20040037802-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | CD44, PAICS, PCBP1 | ALOX15 924/4885TSHR 4112/4885TDP1 955/4885 |
| US-20070166276-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | CD44, PAICS, ALG1 | ALOX15 391/4885TSHR 4153/4885TDP1 1404/4885 |
| US-20060286065-A1 | Releasable polymeric conjugates based on aliphatic biodegradable linkers | CD44, PAICS, PCBP1 | ALOX15 1315/4885TSHR 3944/4885TDP1 1452/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.