Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 15/20 | 0.62 |
| ▸ | CCND1 | P24385 | 7/20 | 0.62 |
| ▸ | PIM1 | P11309 | 3/20 | 0.61 |
| ▸ | DYRK2 | Q92630 | 5/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17489029 | 0.91 | CDK6 (0.62) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17489238 | 0.91 | CDK6 (0.74) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17489295 | 0.88 | CDK6 (0.79) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17488982 | 0.88 | CDK6 (0.69) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17488825 | 0.88 | CDK6 (0.72) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17489032 | 0.84 | CDK6 (0.66) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17489030 | 0.83 | CDK4 (0.65) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17488859 | 0.83 | CDK6 (0.66) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17477168 | 0.81 | CDK6 (0.75) | CDK6CCND1PIM1DYRK2 | |
| SCHEMBL17489122 | 0.81 | CDK4 (0.66) | CDK6CCND1PIM1DYRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015605-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |
| WO-2016015605-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |