Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK6 | Q00534 | 16/20 | 0.74 |
| ▸ | CCND1 | P24385 | 9/20 | 0.74 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.69 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | CDK4 | P11802 | 2/20 | 0.63 |
| ▸ | CCND3 | P30281 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17489295 | 0.92 | CDK6 (0.79) | CDK6CCND1DYRK2PIM1 | |
| SCHEMBL17488982 | 0.92 | CDK6 (0.69) | CDK6CCND1DYRK2PIM1 | |
| SCHEMBL17477157 | 0.91 | CDK6 (0.62) | CDK6CCND1DYRK2PIM1 | |
| SCHEMBL19209837 | 0.90 | CDK6 (0.69) | CDK6CCND1DYRK2PIM1CDK4 | |
| SCHEMBL17477168 | 0.90 | CDK6 (0.75) | CDK6CCND1DYRK2PIM1CDK4 | |
| SCHEMBL17488825 | 0.89 | CDK6 (0.72) | CDK6CCND1DYRK2PIM1 | |
| SCHEMBL19966302 | 0.87 | CDK6 (0.66) | CDK6CCND1DYRK2PIM1CDK4 | |
| SCHEMBL24322965 | 0.85 | CCND1 (1.00) | CDK6CCND1DYRK2CDK4 | |
| SCHEMBL17489122 | 0.84 | CDK4 (0.66) | CDK6CCND1DYRK2PIM1CDK4 | |
| SCHEMBL19966573 | 0.84 | CDK6 (0.64) | CDK6CCND1DYRK2PIM1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016015605-A1 | COMPOUNDS AS CDK SMALL-MOLECULE INHIBITORS AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-02-04 | — | — | WO | disclosed |