Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 6/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | DUSP1 | P28562 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17479006 | 0.85 | SMN1; SMN2 (0.43) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479172 | 0.83 | SMN1; SMN2 (0.42) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479698 | 0.81 | SMN1; SMN2 (0.44) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479795 | 0.79 | SMN1; SMN2 (0.45) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479791 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479697 | 0.77 | MAPK1 (0.38) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479705 | 0.76 | HSD17B10 (0.42) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479057 | 0.73 | PARP3 (0.46) | KDM4EALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL17479324 | 0.73 | TSHR (0.38) | KDM4EALDH1A1NPSR1HPGDMAPK1 | |
| SCHEMBL17479707 | 0.70 | PSEN1 (0.39) | KDM4EALDH1A1NPSR1HPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174859-A1 | FLT3 RECEPTOR ANTAGONISTS | INSERM - Institut National de la Santé et de la Recherche Médicale (FR) | 2017-06-07 | — | — | EP | disclosed |
| WO-2016016370-A1 | FLT3 RECEPTOR ANTAGONISTS | INSERM (Institut National de la Santé et de la Recherche Médicale) (FR) | 2016-02-04 | — | — | WO | disclosed |