SCHEMBL17480107

SCHEMBL17480107

CC(C)(C)[Si](C)(C)Oc1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccc(O[Si](C)(C)C(C)(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 4/20 0.44
CA12 O43570 4/20 0.37
CA1 P00915 4/20 0.37
CA9 Q16790 4/20 0.37
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
MAPT P10636 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
ALOX5 P09917 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16171288 0.86 PREP (0.51) PREPCA12CA1CA9ALDH1A1
SCHEMBL9480558 0.83 PREP (0.40) PREPCA12CA1CA9ALDH1A1
SCHEMBL23491348 0.82 PREP (0.57) PREPCA12CA1CA9KDM4E
SCHEMBL2368966 0.78 PREP (0.45) PREPCA12CA1CA9ALDH1A1
SCHEMBL6763899 0.76 PREP (0.53) PREPCA12CA1CA9ALDH1A1
SCHEMBL2607317 0.75 PREP (0.51) PREPCA12CA1CA9ALDH1A1
SCHEMBL7363983 0.75 PREP (0.54) PREPCA12CA1CA9KDM4E
SCHEMBL20364924 0.75 PREP (0.55) PREPCA12CA1CA9MAPT
Methylamine SCHEMBL7237290 0.75 PREP (0.42) PREPCA12CA1CA9L3MBTL1
SCHEMBL7366758 0.74 PREP (0.50) PREPCA12CA1CA9NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9252381-B2 Organic electronic device and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2016-02-02 US disclosed