SCHEMBL9480558

SCHEMBL9480558

CN(c1ccccc1)c1ccc(N(C)c2ccc(O[Si](C)(C)C(C)(C)C)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PREP P48147 3/20 0.40
CA12 O43570 4/20 0.39
CA1 P00915 4/20 0.39
CA9 Q16790 4/20 0.39
NR3C2 P08235 1/20 0.37
EGFR P00533 2/20 0.36
PDGFRB P09619 2/20 0.36
KDR P35968 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
PIM1 P11309 1/20 0.36
RAB9A P51151 1/20 0.36
CSF1R P07333 2/20 0.35
KDM4C Q9H3R0 1/20 0.35
S1PR4 O95977 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LMNA P02545 1/20 0.34
HSP90AA1 P07900 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9481722 0.87 MTNR1A (0.41) CA12CA1CA9KDRKDM4C
SCHEMBL25351640 0.86 PREP (0.40) PREPCA12CA1CA9ALDH1A1
SCHEMBL9481632 0.83 NR3C2 (0.42) NR3C2EGFRPDGFRBKDRMEN1
SCHEMBL17480107 0.83 PREP (0.44) PREPCA12CA1CA9MEN1
SCHEMBL2368966 0.81 PREP (0.45) PREPCA12CA1CA9ALDH1A1
SCHEMBL9479294 0.80 CSF1R (0.36) NR3C2EGFRPDGFRBKDRMEN1
SCHEMBL17602297 0.80 KDM4C (0.41) PREPCA12CA1CA9KDM4C
SCHEMBL6763899 0.79 PREP (0.53) PREPCA12CA1CA9ALDH1A1
SCHEMBL16171288 0.78 PREP (0.51) PREPCA12CA1CA9NPSR1
Methylamine SCHEMBL7237290 0.77 PREP (0.42) PREPCA12CA1CA9HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5210065-A A mixture of an aromatic amine, an oxidizer and an acid MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-05-11 US disclosed
EP-0479578-A1 Color-forming recording material MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-04-08 EP disclosed