Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22342481 | 0.86 | CREBBP (0.61) | MAOBMAOACREBBPKMT2AALDH1A1 | |
| SCHEMBL18374248 | 0.83 | SMN1; SMN2 (0.52) | MAOBMAOACREBBPKMT2AALDH1A1 | |
| SCHEMBL29387076 | 0.83 | SMN1; SMN2 (0.52) | MAOBMAOACREBBPKMT2AALDH1A1 | |
| SCHEMBL2716561 | 0.82 | MAOB (0.44) | MAOBMAOACREBBPALDH1A1GAA | |
| SCHEMBL17412718 | 0.81 | KMT2A (0.57) | MAOBKMT2AALDH1A1GAASMN1; SMN2 | |
| SCHEMBL18374475 | 0.81 | KDM4E (0.51) | MAOBMAOACREBBPALDH1A1GAA | |
| SCHEMBL26740126 | 0.81 | TTR (0.46) | MAOBMAOACREBBPKMT2AALDH1A1 | |
| SCHEMBL660929 | 0.80 | LMNA (0.55) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL29599043 | 0.80 | LMNA (0.55) | KMT2AALDH1A1GAASMN1; SMN2L3MBTL1 | |
| SCHEMBL18374473 | 0.80 | PDE4B (0.49) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9249145-B2 | Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors | INCYTE HOLDINGS CORPORATION (US) | 2016-02-02 | — | — | US | disclosed |