Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20242670 | 0.81 | HTR6 (0.57) | HTR6HPGDSMN1; SMN2MAPT | |
| SCHEMBL475664 | 0.81 | HPGD (0.65) | HTR6CNR1HPGDSMN1; SMN2MAPT | |
| SCHEMBL5021118 | 0.80 | HTR6 (0.53) | HTR6CNR1HPGDSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL1747995 | 0.80 | HPGD (0.64) | HTR6CNR1HPGDSMN1; SMN2MAPT | |
| SCHEMBL12528587 | 0.79 | HTR6 (0.58) | HTR6CNR1HPGDSMN1; SMN2MAPT | |
| SCHEMBL1747990 | 0.79 | HTR6 (0.68) | HTR6CNR1HPGDSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL1748809 | 0.78 | HTR6 (0.67) | HTR6CNR1HPGDSMN1; SMN2MAPT | |
| SCHEMBL20242549 | 0.78 | HTR6 (0.53) | HTR6HPGDSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL1748852 | 0.77 | HTR6 (0.64) | HTR6CNR1HPGDSMN1; SMN2ADRB1 | |
| SCHEMBL5021159 | 0.77 | HTR6 (0.58) | HTR6CNR1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968538-B2 | Substituted arylamine compounds and methods of treatment | GALENEA CORP. (US) | 2011-06-28 | — | — | US | claimed |