SCHEMBL1748178

SCHEMBL1748178

N#CSCC=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5909191 0.73 ALDH1A1 (0.47)
SCHEMBL5909195 0.73 ALDH1A1 (0.47)
SCHEMBL10824152 0.69
SCHEMBL502289 0.69
SCHEMBL1991366 0.69
Ammonia Solution, Strong SCHEMBL9054746 0.67
SCHEMBL28108365 0.67
SCHEMBL7594449 0.65
SCHEMBL7594448 0.65
SCHEMBL10399353 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6531496-B1 Pesticides in crop protection BAYER AKTIENGESELLSCHAFT (DE) 2003-03-11 US claimed
JP-2002543068-A 2002-12-17 JP claimed
CN-1347412-A aryloxy dithiazole dioxides BAYER AG (DE) 2002-05-01 CN claimed
EP-1173428-A1 O-ARYL DITHIAZOLE DIOXIDES Bayer Aktiengesellschaft (DE) 2002-01-23 EP claimed
WO-2000064881-A1 O-ARYL DITHIAZOLE DIOXIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO claimed
CN-112930342-B Process and intermediates for preparing difluoro sulfones 阿达玛马克西姆有限公司 2024-10-11 CN disclosed
US-11634397-B2 Process and intermediates for the preparation of Fluensulfone ADAMA MAKHTESHIM LTD. (IL) 2023-04-25 US disclosed
US-11351164-B2 Inhibitors of indoleamine 2,3-dioxygenase and methods of their use BRISTOL-MYERS SQUIBB COMPANY (US) 2022-06-07 US disclosed
US-20220002258-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FLUENSULFONE ADAMA MAKHTESHIM LTD. (IL) 2022-01-06 US disclosed
US-20210283123-A1 INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE BRISTOL-MYERS SQUIBB COMPANY 2021-09-16 US disclosed
CN-112930342-A Process and intermediates for preparing difluoride sulfones 阿达玛马克西姆有限公司 2021-06-08 CN disclosed
WO-2020065652-A1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FLUENSULFONE ADAMA MAKHTESHIM LTD. (IL) 2020-04-02 WO disclosed
CN-1816531-A Process for the preparation of aryl alkyl acid derivatives and their use for the treatment of obesity BAYER PHARMACEUTICALS CORP (US) 2006-08-09 CN disclosed
EP-1633722-A2 PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY Bayer Pharmaceuticals Corporation (US) 2006-03-15 EP disclosed
WO-2004100881-A2 PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY BAYER PHARMACEUTICALS CORPORATION (US) 2004-11-25 WO disclosed
US-20040224997-A1 Preparation and use of aryl alkyl acid derivatives for the treatment of obesity BAYER PHARMACEUTICALS CORPORATION 2004-11-11 US disclosed
US-6531496-B1 Pesticides in crop protection BAYER AKTIENGESELLSCHAFT (DE) 2003-03-11 US disclosed
CN-1347412-A aryloxy dithiazole dioxides BAYER AG (DE) 2002-05-01 CN disclosed
EP-1173428-A1 O-ARYL DITHIAZOLE DIOXIDES Bayer Aktiengesellschaft (DE) 2002-01-23 EP disclosed
WO-2000064881-A1 O-ARYL DITHIAZOLE DIOXIDES BAYER AKTIENGESELLSCHAFT (DE) 2000-11-02 WO disclosed