Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.36 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17483882 | 0.94 | PSEN1 (0.34) | TERTPPARGPSEN1PSEN2APH1B | |
| SCHEMBL17483894 | 0.92 | PPARG (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17484032 | 0.90 | PPARG (0.34) | TERTMAPTPPARGPPARACDC25A | |
| SCHEMBL17483954 | 0.90 | CDC25A (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17483876 | 0.89 | PPARG (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL17483878 | 0.87 | PPARG (0.35) | TERTMAPTPPARGPPARACDC25A | |
| SCHEMBL17483956 | 0.87 | CDC25A (0.36) | MEN1KMT2AALDH1A1LMNATERT | |
| SCHEMBL17483942 | 0.86 | CDC25A (0.36) | ALDH1A1LMNAMAPTKDM4EPPARG | |
| SCHEMBL17483952 | 0.86 | TERT (0.34) | MEN1KMT2ATERTKDM4EPPARG | |
| SCHEMBL17190553 | 0.86 | PPARG (0.35) | MAPTPPARGPPARACDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016498-A1 | METHOD FOR PRODUCING PDI DERIVATIVES | UNIVERSIDAD MIGUEL HERNANDEZ DE ELCHE (ES) | 2016-02-04 | — | — | WO | disclosed |