Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 12/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | ILK | Q13418 | 2/20 | 0.47 |
| ▸ | AKR1A1 | P14550 | 4/20 | 0.46 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SCN4A | P35499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20254213 | 0.88 | DYRK1A (0.50) | NPC1GAAMAPK1RAB9ADYRK1A | |
| SCHEMBL10271381 | 0.87 | EPHX2 (0.59) | NPC1GAAMAPK1RAB9ADYRK1A | |
| SCHEMBL14791428 | 0.85 | NPC1 (0.59) | NPC1GAAMAPK1RAB9ADYRK1A | |
| SCHEMBL5632209 | 0.84 | DYRK1A (0.50) | DYRK1AAKR1B1TRPV1ILKAKR1A1 | |
| SCHEMBL359623 | 0.84 | DYRK1A (0.49) | DYRK1AAKR1B1TRPV1ILKAKR1A1 | |
| SCHEMBL360373 | 0.84 | DYRK1A (0.49) | DYRK1AAKR1B1TRPV1ILKAKR1A1 | |
| SCHEMBL3265720 | 0.84 | LOXL2 (0.59) | DYRK1AAKR1B1TRPV1ILKAKR1A1 | |
| SCHEMBL7082892 | 0.84 | DYRK1A (0.49) | DYRK1AAKR1B1TRPV1ILKAKR1A1 | |
| SCHEMBL20964606 | 0.83 | DYRK1A (0.49) | DYRK1AAKR1B1TRPV1ILKAKR1A1 | |
| Hydrochloric Acid SCHEMBL15708092 | 0.83 | DYRK1A (0.48) | DYRK1AAKR1B1TRPV1ILKAKR1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970158-B1 | ALKYL-HETEROARYL SUBSTITUTED QUINONE DERIVATIVES FOR TREATMENT OF OXIDATIVE STRESS DISORDERS | BIOELECTRON TECH CORP (US) | 2019-02-20 | — | — | EP | disclosed |
| WO-2016019233-A1 | INHIBITORS OF BRUTON'S TYROSINE KINASE | PHARMACYCLICS LLC (US) | 2016-02-04 | — | — | WO | disclosed |