Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 3/20 | 0.35 |
| ▸ | RARA | P10276 | 2/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.33 |
| ▸ | MMP12 | P39900 | 3/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17484399 | 0.88 | POLB (0.39) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL17484413 | 0.87 | POLB (0.40) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL17484437 | 0.86 | RARB (0.36) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL17484362 | 0.84 | POLB (0.35) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL18194827 | 0.83 | RARB (0.44) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL22131036 | 0.82 | THRB (0.41) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL17484436 | 0.82 | RARB (0.36) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL22459521 | 0.82 | RARB (0.38) | POLBAPEX1HTTTDP1RARB | |
| SCHEMBL19854252 | 0.81 | RARB (0.39) | RARBRARARARGTSHRS1PR1 | |
| SCHEMBL17484400 | 0.81 | RARB (0.37) | RARBRARARARGS1PR1MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3174955-B1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2019-10-23 | — | — | EP | disclosed |
| US-10294426-B2 | Liquid crystalline media having homeotropic alignment | MERCK PATENT GMBH (DE) | 2019-05-21 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20180208848-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| WO-2016015803-A1 | LIQUID CRYSTALLINE MEDIA HAVING HOMEOTROPIC ALIGNMENT | MERCK PATENT GMBH (DE) | 2016-02-04 | — | — | WO | disclosed |