Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26508171 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL26508178 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL26508419 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL9548202 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL9548200 | 0.90 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL7519156 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL7519164 | 0.90 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL9548201 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL9548205 | 0.87 | SMN1; SMN2 (0.51) | SMN1; SMN2MEN1KMT2APOLBPRCP | |
| SCHEMBL5101105 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2MEN1KMT2APOLBPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016168-A1 | COMPOSITION FOR MODULATING THE ACTIVITY OF NON-STRUCTURAL PROTEINS | EBERHARD KARLS UNIVERSITAET TUEBINGEN MEDIZINISCHE FAKULTAET (DE) | 2016-02-04 | — | — | WO | disclosed |