Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.92 |
| ▸ | HPGD | P15428 | 1/20 | 0.92 |
| ▸ | MAPT | P10636 | 14/20 | 0.82 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.82 |
| ▸ | HTR6 | P50406 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.66 |
| ▸ | HTT | P42858 | 4/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1748841 | 0.99 | SMN1; SMN2 (0.90) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| SCHEMBL2483491 | 0.96 | SMN1; SMN2 (1.00) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| Hydrochloric Acid SCHEMBL1748355 | 0.95 | SMN1; SMN2 (0.98) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| SCHEMBL20242208 | 0.90 | SMN1; SMN2 (0.74) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| Tert-Butyl Formate SCHEMBL27724335 | 0.87 | SMN1; SMN2 (0.82) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| SCHEMBL475554 | 0.85 | SMN1; SMN2 (0.80) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| SCHEMBL20241586 | 0.85 | HPGD (0.80) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| SCHEMBL475719 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| SCHEMBL475396 | 0.85 | SMN1; SMN2 (0.79) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 | |
| Hydrochloric Acid SCHEMBL1748265 | 0.84 | SMN1; SMN2 (0.79) | SMN1; SMN2HPGDMAPTALDH1A1HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7968538-B2 | Substituted arylamine compounds and methods of treatment | GALENEA CORP. (US) | 2011-06-28 | — | — | US | claimed |
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | BECKER OREN (IL) | 2012-05-10 | — | — | US | disclosed |
| US-7968538-B2 | Substituted arylamine compounds and methods of treatment | GALENEA CORP. (US) | 2011-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120115850-A1 | SUBSTITUTED ARYLAMINE COMPOUNDS AND METHODS OF TREATMENT | HTR6, HTR2A, HTR3B | SMN1; SMN2 3858/4885HPGD 2326/4885MAPT 4350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.