Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.60 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.47 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.47 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.47 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.47 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736116 | 0.88 | TLR8 (0.54) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL18239639 | 0.86 | TLR8 (0.49) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL9736014 | 0.86 | TLR8 (0.49) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL19422763 | 0.86 | TLR8 (0.49) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL30038381 | 0.86 | TLR8 (0.49) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL187674 | 0.86 | MEN1 (0.52) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL187054 | 0.86 | TLR8 (0.55) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL1544861 | 0.85 | TLR8 (0.48) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL7043680 | 0.85 | TNFSF11 (0.51) | TLR8TLR7MEN1POLBMAPK1 | |
| SCHEMBL17429741 | 0.85 | PDE3B (0.50) | TLR8TLR7MEN1POLBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 400 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620885-B | Poly R-indole blue light absorber and preparation method and application thereof | 华东理工大学 | 2023-05-30 | — | — | CN | claimed |
| EP-2582351-B1 | HAIR DYEING PROCESS USING A COMPOSITION COMPRISING AT LEAST ONE INDOLE OR INDOLINE COMPOUND, A METAL SALT, HYDROGEN PEROXIDE AND A BASIFYING AGENT | L'ORÉAL (FR) | 2017-08-02 | — | — | EP | claimed |
| CN-1079395-C | Production method of N-acetyl-5, 6-dimethoxytryptamine | TAN DUNXIAN (CN) | 2002-02-20 | — | — | CN | claimed |
| EP-0547065-B1 | MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS | LARGE SCALE BIOLOGY CORP (US) | 2001-08-29 | — | — | EP | claimed |
| CN-1042393-C | Application of indole derivatives in dyeing of keratose fibre as colour | OREAL (FR) | 1999-03-10 | — | — | CN | claimed |
| US-5874091-A | PROTECTION OF SKIN AND HAIR AGAINST ULTRAVIOLET RADIATION AND FOR PIGMENTATION OF THE SKIN AND HAIR; HOMOGENEOUS AQUEOUS DISPERSION OF LAMELLAR AND ENCAPSULATING VESICLES; STORAGE STABILITY; STORING MELANIN PIGMENT IN THE STRATUM CORNEUM. | L'OREAL (FR) | 1999-02-23 | — | — | US | claimed |
| CN-1191219-A | Melatonin derivative, its preparation, production process and its application in medicine | TAN DUNXIAN (CN) | 1998-08-26 | — | — | CN | claimed |
| EP-0587837-B1 | Cosmetic composition containing melanistic pigments in association with certain tocopherols, and method for protecting the skin, the hair, the mucous membranes and cosmetic compositions | OREAL (FR) | 1998-06-03 | — | — | EP | claimed |
| EP-0544874-B1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | OREAL (FR) | 1998-04-08 | — | — | EP | claimed |
| US-5695747-A | APPLYING TO THE SKIN OR HAIR AND ULTRAVIOLET PROETECTION AGENT | L'OREAL (FR) | 1997-12-09 | — | — | US | claimed |
| US-5205837-A | Formed in situ by oxidation of indole compound | L'OREAL (FR) | 1993-04-27 | — | — | US | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0518773-A1 | Cosmetic composition containing a blend of metallic oxids nanopigments and melanic pigments | L'OREAL (FR) | 1992-12-16 | — | — | EP | claimed |
| EP-0504347-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS. | OREAL (FR) | 1992-09-23 | — | — | EP | claimed |
| CN-1063409-A | Indole derivatives is done the application of colour former in the dyeing keratinous fibres process | OREAL (FR) | 1992-08-12 | — | — | CN | claimed |
| EP-0496653-A1 | Use of indol derivatives as coupling agents in dyeing of keratin fibres | L'OREAL (FR) | 1992-07-29 | — | — | EP | claimed |
| WO-1992005761-A1 | COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS | L'OREAL (FR) | 1992-04-16 | — | — | WO | claimed |
| EP-0467767-A1 | Product based on flaky particles containing melanine pigment and process for their preparation | L'OREAL (FR) | 1992-01-22 | — | — | EP | claimed |
| WO-1992000373-A1 | MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS | BIOSOURCE GENETICS CORPORATION (CA) | 1992-01-09 | — | — | WO | claimed |
| EP-0441689-A1 | Process for enzymatic preparation of melanin pigment and its use in cosmetics | L'OREAL (FR) | 1991-08-14 | — | — | EP | claimed |