Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.39 |
| ▸ | TYMS | P04818 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17487684 | 0.85 | RAB9A (0.53) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL17487479 | 0.83 | RAB9A (0.39) | RAB9ASMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL17487837 | 0.82 | RAB9A (0.48) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL18960452 | 0.81 | NPC1 (0.46) | RAB9ASMN1; SMN2MAPTPOLBHDAC1 | |
| SCHEMBL17487452 | 0.79 | RAB9A (0.47) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL17487489 | 0.79 | RAB9A (0.44) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL17488221 | 0.77 | SMN1; SMN2 (0.49) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL17488113 | 0.77 | RAB9A (0.44) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL17487331 | 0.77 | RAB9A (0.45) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B | |
| SCHEMBL17488111 | 0.77 | RAB9A (0.48) | RAB9ASMN1; SMN2TP53GRIN1GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |