Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | TEK | Q02763 | 1/20 | 0.40 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17488200 | 0.91 | RAB9A (0.42) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17488040 | 0.90 | RAB9A (0.45) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17487327 | 0.88 | RAB9A (0.45) | RAB9ASMN1; SMN2TP53LMNAHTT | |
| SCHEMBL17487684 | 0.85 | RAB9A (0.53) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17488199 | 0.85 | RAB9A (0.56) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17488095 | 0.82 | RAB9A (0.49) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17487354 | 0.81 | RAB9A (0.57) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17488284 | 0.81 | POLB (0.46) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17488111 | 0.81 | RAB9A (0.48) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 | |
| SCHEMBL17488215 | 0.81 | RAB9A (0.48) | GRIN1GRIN2BRAB9ASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |