Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | FNTA | P49354 | 2/20 | 0.39 |
| ▸ | FNTB | P49356 | 2/20 | 0.39 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15705100 | 0.82 | SLC6A2 (0.57) | SLC6A3SLC6A2SLC6A4LMNACHRM2 | |
| SCHEMBL12925888 | 0.81 | SLC6A3 (0.49) | SLC6A3SLC6A2SLC6A4LMNACHRM2 | |
| SCHEMBL18965803 | 0.79 | TSHR (0.48) | CYP19A1FNTAFNTBPGGT1BHTT | |
| SCHEMBL15866163 | 0.78 | SLC6A3 (0.48) | SLC6A3SLC6A2SLC6A4LMNACHRM2 | |
| SCHEMBL7385564 | 0.78 | CYP2A6 (0.46) | CYP2C19GAACYP19A1HTTKDM4E | |
| SCHEMBL17488165 | 0.76 | SLC6A2 (0.42) | SLC6A3SLC6A2SLC6A4MEN1GAA | |
| SCHEMBL9168089 | 0.76 | SLC6A2 (0.42) | SLC6A3SLC6A2SLC6A4CHRM2ADRA2B | |
| SCHEMBL17488161 | 0.76 | SLC6A3 (0.45) | SLC6A3SLC6A2SLC6A4LMNACHRM2 | |
| SCHEMBL10363179 | 0.72 | SLC6A2 (0.40) | SLC6A3SLC6A2SLC6A4LMNACHRM2 | |
| SCHEMBL10363180 | 0.72 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016016421-A1 | 2-AMINO-BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS 5-LIPOXYGENASE AND/OR PROSTAGLANDIN E SYNTHASE INHIBITORS | INSTITUT PASTEUR KOREA (KR) | 2016-02-04 | — | — | WO | disclosed |