Estradiol Benzoate

Estradiol Benzoate

SCHEMBL174896

C[C@]12CC[C@@H]3c4ccc(OC(=O)c5ccccc5)cc4CC[C@H]3[C@@H]1CC[C@@H]2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 1.00
LMNA P02545 5/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
ADORA3 P0DMS8 2/20 1.00
ATM Q13315 2/20 1.00
NR3C1 P04150 2/20 1.00
SHBG P04278 2/20 1.00
SLC6A4 P31645 2/20 1.00
HTR2B P41595 2/20 1.00
KMT2A Q03164 2/20 1.00
FYN P06241 1/20 1.00
ADRA2C P18825 1/20 1.00
SLC6A2 P23975 1/20 1.00
HTT P42858 1/20 1.00
PGR P06401 2/20 0.77
AR P10275 2/20 0.77
SLC6A3 Q01959 2/20 0.77
CHRM1 P11229 1/20 0.77
TBXA2R P21731 1/20 0.77
ADRA1A P35348 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Estradiol Benzoate SCHEMBL22049057 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL29486378 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL18467889 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL14360474 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL12187133 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL12180364 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL301616 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL9320465 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL20770923 0.99 ESR1 (0.98) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL5885955 0.96 ESR1 (0.93) ESR1LMNASMN1; SMN2ADORA3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7024 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260076978-A1 COMPOSITIONS FOR NON-SURGICAL PREVENTION OF BOAR TAINT AND AGGRESSIVE BEHAVIOR INSIGNA INC (US) 2026-03-19 US claimed
EP-4674894-A2 COPOLYMERS OF N-VINYLPYRROLIDONE WITH FUNCTIONALIZED MALEIC ACID MOIETIES Hemoteq AG (DE) 2026-01-07 EP claimed
EP-4663688-A2 CROSSLINKERS Hemoteq AG (DE) 2025-12-17 EP claimed
US-12310928-B2 Enthesis healing UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-05-27 US claimed
CN-119792305-A Estradiol benzoate as sterilant 因斯格纳公司 2025-04-11 CN claimed
EP-4531594-A1 PREVENTION OF ESTRUS IN SOW AND RUMINANTS Insigna Inc. (US) 2025-04-09 EP claimed
CN-119701013-A Estrogen-beta-cyclodextrin inclusion compound, preparation method thereof and tablets 浙江仙琚制药股份有限公司 2025-03-28 CN claimed
CN-119504907-A Synthesis method of estradiol benzoate 华中药业股份有限公司 2025-02-25 CN claimed
CN-115825281-B Curcuma wenyujin and vinegar product quality evaluation method thereof 南京中医药大学 2024-12-20 CN claimed
CN-118731240-A Method for detecting hormone and suspected endocrine disruptors in water body by taking effect as guide 国科大杭州高等研究院 2024-10-01 CN claimed
US-4402695-A Device for delivering agent in vagina ALZA CORPORATION (US) 1983-09-06 US claimed
US-4383993-A PROGESTERONE, ESTRADIOL AND ESTERS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1983-05-17 US claimed
EP-0015637-B1 METHOD FOR ENHANCING GROWTH RATE AND FEED EFFICIENCY OF RUMINANTS AMERICAN CYANAMID COMPANY (US) 1983-03-09 EP claimed
US-4321252-A Polymeric diffusion matrix containing ester derivatives of estradiol KEY PHARMACEUTICALS, INC. (US) 1982-03-23 US claimed
US-4315925-A MAMMALIAN CONTRACEPTIVES COMPRISING PROGESTERONE AND 17B-ESTRADIOL UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 1982-02-16 US claimed
US-4259320-A SYNERGISTIC; STEROIDS; EFFICIENT UTILIZATION OF FEEDS AMERICAN CYANAMID COMPANY (US) 1981-03-31 US claimed
EP-0015637-A1 Method for enhancing growth rate and feed efficiency of ruminants AMERICAN CYANAMID COMPANY (US) 1980-09-17 EP claimed
US-4180560-A Inert core implant pellet SYNTEX CORPORATION (US) 1979-12-25 US claimed
US-4096239-A Inert core implant pellet SYNTEX CORPORATION (PM) 1978-06-20 US claimed
US-3962430-A Sterilization of solid non-electrolyte medicinal agents employing sodium chloride MERCK & CO., INC. (US) 1976-06-08 US claimed