Estradiol Benzoate

Estradiol Benzoate

SCHEMBL29486378

C[C@]12CC[C@@H]3c4ccc(OC(=O)c5ccccc5)cc4CC[C@H]3[C@@H]1CC[C@@H]2O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 1.00
LMNA P02545 5/20 1.00
SMN1; SMN2 Q16637 4/20 1.00
ADORA3 P0DMS8 2/20 1.00
ATM Q13315 2/20 1.00
NR3C1 P04150 2/20 1.00
SHBG P04278 2/20 1.00
SLC6A4 P31645 2/20 1.00
HTR2B P41595 2/20 1.00
KMT2A Q03164 2/20 1.00
FYN P06241 1/20 1.00
ADRA2C P18825 1/20 1.00
SLC6A2 P23975 1/20 1.00
HTT P42858 1/20 1.00
PGR P06401 2/20 0.77
AR P10275 2/20 0.77
SLC6A3 Q01959 2/20 0.77
CHRM1 P11229 1/20 0.77
TBXA2R P21731 1/20 0.77
ADRA1A P35348 1/20 0.77

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Estradiol Benzoate SCHEMBL22049057 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL18467889 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL14360474 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL12187133 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL174896 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL12180364 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL301616 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL9320465 1.00 ESR1 (1.00) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL20770923 0.99 ESR1 (0.98) ESR1LMNASMN1; SMN2ADORA3ATM
Estradiol Benzoate SCHEMBL5885955 0.96 ESR1 (0.93) ESR1LMNASMN1; SMN2ADORA3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3089732-B1 CONTROLLED RELEASE FATTY ACID COMPOSITIONS FOR USE IN BODY RECONSTRUCTION AND BODY-SHAPING PB&B SA (CH) 2023-09-27 EP claimed
EP-3886816-B1 ESTRADIOL BENZOATE AS A STERILANT INSIGNA INC (US) 2023-09-13 EP claimed
EP-2040683-B2 PHARMACEUTICAL COMPOSITION CONTAINING A TETRAHYDROFOLIC ACID BAYER IP GMBH (DE) 2023-08-16 EP claimed
CN-112423590-B Mixtures and use comprising benzpyrimoxan and oxazosulfyl and methods for their application 巴斯夫欧洲公司 2022-07-08 CN claimed
EP-3616756-B1 COMPOSITION FOR PROMOTING HAIR GROWTH, USE OF THE HAIR GROWTH AGENT AND METHOD FOR PRODUCING THE SAME MUELLER KAEHMANN DIETER KLAUS (DE) 2022-03-09 EP claimed
EP-4747409-A2 COLLECTION, ASSESSMENT AND EARLY DETECTION OF HUMAN LUNG CANCER BIOMARKERS IN EXHALED BREATH CONDENSATES OF MOUSE ANIMAL MODELS Hackensack Meridian Health, Inc. (US) 2026-05-27 EP disclosed
EP-4673465-A1 ANTI-NETRIN-1 MONOCLONAL ANTIBODY FOR TREATING ENDOMETRIOSIS AND ASSOCIATED PAINS South Australian Health and Medical Research Institute Limited (AU) 2026-01-07 EP disclosed
US-12429485-B2 Biomarker panels for on-treatment prediction of response to immuno-oncology drugs THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2025-09-30 US disclosed
US-12383132-B2 Identification and control of myopic progression using distortion ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-08-12 US disclosed
US-20250223567-A1 COMPOSITIONS AND METHODS FOR OBTAINING VASCULARIZED HUMAN INTESTINAL ORGANOID TISSUE, AND RELATED USES THEREOF THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2025-07-10 US disclosed
EP-4580644-A1 ADVANCED ALVEOLAR EPITHELIAL ORGANOIDS Children's Hospital Medical Center (US) 2025-07-09 EP disclosed
US-20250057873-A1 Intestinal Tumor Suppressor, PGE2 Production Inhibitor, and IL-22BP Production Promoter LOUIS PASTEUR CENTER FOR MEDICAL RESEARCH (JP) 2025-02-20 US disclosed
EP-4039589-A1 HULL SYSTEM AND AIRCRAFT Airbus Helicopters (FR) 2022-08-10 EP disclosed
WO-2022140386-A1 DETECTION OF LUNG CANCER USING CELL-FREE DNA FRAGMENTATION THE JOHNS HOPKINS UNIVERSITY (US) 2022-06-30 WO disclosed
CN-114641496-A Multispecific binding proteins for cancer therapy 勃林格殷格翰国际有限公司 2022-06-17 CN disclosed
CN-114554857-A Baked good composition comprising psicose 玉米产品开发公司 2022-05-27 CN disclosed
CN-114423748-A Novel heteroaryl triazole compounds as pesticides 拜耳公司 2022-04-29 CN disclosed
CN-114213510-A Modified Cry1Ca toxins useful for controlling insect pests 美国陶氏益农公司 2022-03-22 CN disclosed
CN-114177225-A Application of oyster and kudzu root compound traditional Chinese medicine composition in aspect of treating/preventing hyperlipidemia 广西医科大学 2022-03-15 CN disclosed
WO-2022040202-A1 B-CELL BASED IMMUNOTHERAPY FOR THE TREATMENT OF GLIOBLASTOMA AND OTHER CANCERS NORTHWESTERN UNIVERSITY (US) 2022-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057873-A1 Intestinal Tumor Suppressor, PGE2 Production Inhibitor, and IL-22BP Production Promoter ILF2, PTGS1, IL36G ESR1 4703/4885LMNA 3753/4885SMN1; SMN2 4882/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.