Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.35 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17490363 | 0.97 | L3MBTL1 (0.50) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL16132528 | 0.95 | SMN1; SMN2 (0.48) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL17490358 | 0.93 | SMN1; SMN2 (0.53) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL16132356 | 0.83 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL16132365 | 0.80 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL21742299 | 0.79 | SMN1; SMN2 (0.41) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL21742307 | 0.79 | SMN1; SMN2 (0.41) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL21742263 | 0.79 | SMN1; SMN2 (0.46) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL16132530 | 0.79 | SMN1; SMN2 (0.46) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 | |
| SCHEMBL21742194 | 0.77 | SMN1; SMN2 (0.47) | L3MBTL1SMN1; SMN2CHRM3CHRM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-20160031868-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | GILEAD SCIENCES, INC. | 2016-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160031868-A1 | BENZIMIDAZOLONE DERIVATIVES AS BROMODOMAIN INHIBITORS | BRD4, BRD3, BRD1 | L3MBTL1 1346/4885SMN1; SMN2 3186/4885CHRM3 2978/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.