Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | KDM1A | O60341 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 6/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 6/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17494206 | 1.00 | KCNH2 (0.54) | KCNH2KDM1AALDH1A1POLBCHRM2 | |
| Hydrochloric Acid SCHEMBL19179918 | 0.99 | KCNH2 (0.53) | KCNH2KDM1AALDH1A1POLBCHRM2 | |
| SCHEMBL19194962 | 0.88 | KCNH2 (0.54) | KCNH2KDM1AALDH1A1 | |
| SCHEMBL17494440 | 0.84 | KCNH2 (0.49) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL17494442 | 0.84 | KCNH2 (0.49) | KCNH2ALDH1A1POLBCHRM2CHRM1 | |
| SCHEMBL17494385 | 0.81 | ALDH1A1 (0.42) | KCNH2KDM1AALDH1A1POLBCHRM2 | |
| SCHEMBL17494387 | 0.81 | ALDH1A1 (0.42) | KCNH2KDM1AALDH1A1POLBCHRM2 | |
| SCHEMBL1381572 | 0.78 | ALDH1A1 (0.43) | KCNH2KDM1AALDH1A1POLBCHRM2 | |
| SCHEMBL19200972 | 0.78 | KCNH2 (0.45) | KCNH2OPRM1OPRD1PIM1PIM3 | |
| Hydrochloric Acid SCHEMBL4524403 | 0.78 | ALDH1A1 (0.42) | KCNH2KDM1AALDH1A1POLBCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10160726-B2 | Quinolone derivatives as antibacterials | NOVARTIS AG (CH) | 2018-12-25 | — | — | US | claimed |
| EP-3177593-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | Novartis AG (CH) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016020836-A1 | QUINOLONE DERIVATIVES AS ANTIBACTERIALS | NOVARTIS AG (CH) | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10160726-B2 | Quinolone derivatives as antibacterials | TOP1, NQO2, TOP2A | KCNH2 3467/4885KDM1A 1130/4885ALDH1A1 1836/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.