SCHEMBL1749709

SCHEMBL1749709

CS(=O)(=O)c1ccc(C(=O)O)n1-c1ncccc1Cl

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MYC P01106 2/20 0.40
HSD11B1 P28845 3/20 0.38
TRPV1 Q8NER1 2/20 0.37
MALT1 Q9UDY8 2/20 0.37
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TRPA1 O75762 2/20 0.34
PKM P14618 1/20 0.34
DHODH Q02127 1/20 0.34
KCNH2 Q12809 1/20 0.34
TRPM8 Q7Z2W7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL950453 0.83 MYC (0.42) MYCTRPV1MALT1LMNASMN1; SMN2
SCHEMBL951449 0.78 MYC (0.43) MYCTRPV1MALT1LMNASMN1; SMN2
SCHEMBL951576 0.78 MYC (0.40) MYCTRPV1MALT1LMNASMN1; SMN2
SCHEMBL953674 0.77 MYC (0.40) MYCTRPV1MALT1LMNASMN1; SMN2
SCHEMBL950452 0.74 HSD11B1 (0.37) MYCHSD11B1MALT1LMNASMN1; SMN2
SCHEMBL951737 0.73 MYC (0.41) MYCTRPV1MALT1LMNASMN1; SMN2
SCHEMBL27727954 0.73 MALT1 (0.36) MYCMALT1LMNASMN1; SMN2TRPA1
SCHEMBL950795 0.72 MALT1 (0.36) MYCMALT1LMNASMN1; SMN2TRPA1
SCHEMBL951317 0.70 MYC (0.38) MYCMALT1LMNASMN1; SMN2TRPA1
SCHEMBL951105 0.70 MYC (0.38) MYCMALT1LMNASMN1; SMN2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968573-B2 Hydrazide compound and pesticidal use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-06-28 US disclosed
EP-1937664-B1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2011-06-15 EP disclosed
EP-2251336-A1 Hydrazide compounds as intermediates of pesticides Sumitomo Chemical Company, Limited (JP) 2010-11-17 EP disclosed
EP-1937664-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2008-07-02 EP disclosed
WO-2007043677-A9 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL CO (JP) 2007-06-07 WO disclosed
WO-2007043677-A1 HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-19 WO disclosed