Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | FPR1 | P21462 | 1/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL173431 | 0.90 | CTSA (0.33) | CTSA | |
| SCHEMBL176222 | 0.88 | MEN1 (0.33) | BRD4HSD17B10CRHR1CTSAFPR1 | |
| SCHEMBL174373 | 0.88 | RAB9A (0.33) | RAB9ABRD4HSD17B10MGLLPOLB | |
| SCHEMBL175095 | 0.88 | RAB9A (0.33) | RAB9ABRD4HSD17B10MGLLPOLB | |
| SCHEMBL173710 | 0.85 | MEN1 (0.35) | ALDH1A1SMN1; SMN2GAACTSAMEN1 | |
| SCHEMBL174378 | 0.81 | NR3C2 (0.39) | CTSA | |
| SCHEMBL173488 | 0.80 | PRKDC (0.35) | BRD4HSD17B10MGLLTSHRFPR1 | |
| SCHEMBL174146 | 0.79 | MEN1 (0.33) | BRD4HSD17B10CRHR1FPR1FPR2 | |
| SCHEMBL174348 | 0.77 | NR3C2 (0.38) | CTSA | |
| SCHEMBL174422 | 0.76 | MEN1 (0.37) | BRD4POLBALDH1A1CRHR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611297-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-06-17 | — | — | EP | claimed |
| US-8754115-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-17 | — | — | US | claimed |
| EP-2611297-A1 | FUNGICIDAL PYRAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | claimed |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | claimed |
| WO-2012030922-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | claimed |
| US-9131693-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-15 | — | — | US | disclosed |
| EP-2611297-B1 | FUNGICIDAL PYRAZOLES | DU PONT (US) | 2015-06-17 | — | — | EP | disclosed |
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-08-07 | — | — | US | disclosed |
| US-8754115-B2 | Fungicidal pyrazoles | E I DU PONT DE NEMOURS AND COMPANY (US) | 2014-06-17 | — | — | US | disclosed |
| EP-2611297-A1 | FUNGICIDAL PYRAZOLES | E.I. Du Pont De Nemours And Company (US) | 2013-07-10 | — | — | EP | disclosed |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2012030922-A1 | FUNGICIDAL PYRAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221448-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | RAB9A 620/4885BRD4 3081/4885HSD17B10 1514/4885 |
| US-20130143940-A1 | FUNGICIDAL PYRAZOLES | CYP1A1, CYP1B1, CYP4X1 | RAB9A 620/4885BRD4 3081/4885HSD17B10 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.