Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17515347 | 1.00 | KMT2A (0.36) | KMT2ACYP3A4CYP2D6SMN1; SMN2CA1 | |
| SCHEMBL17497892 | 0.84 | SMN1; SMN2 (0.37) | KMT2ACYP3A4CYP2D6SMN1; SMN2DDB1 | |
| SCHEMBL17515369 | 0.81 | KDM4E (0.40) | — | |
| SCHEMBL17497188 | 0.81 | KDM4E (0.40) | — | |
| SCHEMBL17515374 | 0.81 | L3MBTL1 (0.36) | CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL17497185 | 0.81 | L3MBTL1 (0.36) | CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL17497348 | 0.81 | L3MBTL1 (0.36) | CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL17497183 | 0.81 | L3MBTL1 (0.36) | CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL17515375 | 0.81 | L3MBTL1 (0.36) | CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL17515356 | 0.79 | KMT2A (0.43) | KMT2ACA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-02-18 | — | — | US | disclosed |
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | MASSACHUSETTS INST TECHNOLOGY (US) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160046590-A1 | SONIC HEDGEHOG MODULATORS | SHH, GLI1, SMO | KMT2A 1803/4885CYP3A4 4881/4885CYP2D6 4875/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.