SCHEMBL17498587

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17498588	1.00	ERBB2 (0.80)	ERBB2EGFRERBB4JAK3ABL1
	SCHEMBL2512027	0.91	EGFR (0.85)	ERBB2EGFRERBB4JAK3ABL1
	Allitinib SCHEMBL29354831	0.89	EGFR (1.00)	ERBB2EGFRERBB4ABL1INSR
	Allitinib SCHEMBL31732812	0.89	EGFR (1.00)	ERBB2EGFRERBB4ABL1INSR
	Allitinib SCHEMBL233985	0.89	EGFR (1.00)	ERBB2EGFRERBB4ABL1INSR
	SCHEMBL17498589	0.88	EGFR (0.76)	ERBB2EGFRERBB4JAK3
	SCHEMBL17498590	0.88	EGFR (0.76)	ERBB2EGFRERBB4JAK3
	Allitinib SCHEMBL1402417	0.88	EGFR (0.98)	ERBB2EGFRERBB4ABL1INSR
	SCHEMBL17498548	0.88	EGFR (0.81)	ERBB2EGFRERBB4JAK3
	SCHEMBL17498545	0.88	EGFR (0.81)	ERBB2EGFRERBB4JAK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.