Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | LDHA | P00338 | 1/20 | 0.30 |
| ▸ | LDHB | P07195 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499115 | 0.89 | KDM4E (0.40) | KDM4ECYP2D6MAPTKMT2AMEN1 | |
| SCHEMBL16097200 | 0.79 | MEN1 (0.36) | KDM4EKMT2AMEN1TAAR1 | |
| SCHEMBL16102684 | 0.77 | KDM4E (0.49) | KDM4EMAPTKMT2AMEN1LMNA | |
| SCHEMBL16097924 | 0.77 | MEN1 (0.32) | KMT2AMEN1TAAR1 | |
| SCHEMBL16103515 | 0.77 | MAOA (0.42) | KMT2AMEN1TAAR1LMNA | |
| SCHEMBL17499346 | 0.76 | MEN1 (0.33) | KMT2AMEN1TAAR1 | |
| SCHEMBL17499352 | 0.76 | MEN1 (0.30) | KMT2AMEN1TAAR1 | |
| SCHEMBL16102679 | 0.76 | KMT2A (0.41) | KDM4EMAPTKMT2AMEN1TAAR1 | |
| SCHEMBL17499495 | 0.74 | MEN1 (0.35) | KMT2AMEN1TAAR1 | |
| SCHEMBL16095979 | 0.74 | MEN1 (0.33) | KMT2AMEN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |