Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16096024 | 0.87 | ALDH1A1 (0.38) | GRM5ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL16098051 | 0.86 | HTT (0.33) | GRM5ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL17499257 | 0.85 | GRM5 (0.38) | GRM5ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17499299 | 0.84 | GRM5 (0.33) | GRM5ALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL17499301 | 0.82 | TDP1 (0.37) | ALDH1A1HTTLMNASMN1; SMN2ESR1 | |
| SCHEMBL16098223 | 0.81 | TBXA2R (0.46) | HTTLMNASMN1; SMN2KDM4E | |
| SCHEMBL16097616 | 0.80 | ALDH1A1 (0.34) | ALDH1A1HTTLMNASMN1; SMN2ESR1 | |
| SCHEMBL16097113 | 0.79 | TBXA2R (0.40) | ALDH1A1HTTESR1ESR2GAA | |
| SCHEMBL16097932 | 0.79 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2ESR1ESR2GAA | |
| SCHEMBL17499543 | 0.78 | TDP1 (0.31) | ESR1ESR2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |