Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499264 | 1.00 | KMT2A (0.49) | KMT2AALDH1A1MEN1GAAGRIN1 | |
| SCHEMBL17499341 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1GAASMN1; SMN2 | |
| SCHEMBL17499167 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1GAASMN1; SMN2 | |
| SCHEMBL17499164 | 0.86 | ALDH1A1 (0.44) | KMT2AALDH1A1MEN1GAASMN1; SMN2 | |
| SCHEMBL16097841 | 0.86 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1GAAGRIN1 | |
| SCHEMBL16095645 | 0.86 | GRIN1 (0.46) | KMT2AALDH1A1MEN1GAAGRIN1 | |
| SCHEMBL16095643 | 0.86 | GRIN1 (0.46) | KMT2AALDH1A1MEN1GAAGRIN1 | |
| SCHEMBL16098404 | 0.84 | GRIN1 (0.50) | KMT2AALDH1A1MEN1GAAGRIN1 | |
| SCHEMBL16098403 | 0.84 | GRIN1 (0.50) | KMT2AALDH1A1MEN1GAAGRIN1 | |
| SCHEMBL16097016 | 0.80 | POLB (0.46) | KMT2AALDH1A1MEN1GAAGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| CN-105209268-B | Heterocyclic imine functionalized polymers | 株式会社普利司通 | 2018-05-04 | — | — | CN | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |