SCHEMBL17499334

SCHEMBL17499334

Cc1ccc(C=Nc2ccccc2O[SiH](C)C)nc1

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.33
KDM4E B2RXH2 5/20 0.33
USP2 O75604 2/20 0.33
GAA P10253 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HPGD P15428 2/20 0.32
HSD17B10 Q99714 1/20 0.32
PLA2G1B P04054 1/20 0.32
MAPT P10636 1/20 0.32
ATG4B Q9Y4P1 1/20 0.32
POLB P06746 1/20 0.31
NR4A1 P22736 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16096586 0.85 ALDH1A1 (0.42) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL16096588 0.85 ALDH1A1 (0.42) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL17499748 0.84 KDM4E (0.30) ALDH1A1KDM4EGAAMEN1KMT2A
SCHEMBL17499263 0.83 KDM4E (0.32) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL17499433 0.82 ALDH1A1 (0.35) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL17499431 0.82 ALDH1A1 (0.35) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL17499571 0.82 NR4A1 (0.50) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL17499681 0.80 KDM4E (0.34) ALDH1A1KDM4EUSP2GAAMEN1
SCHEMBL17499781 0.79 KDM4E (0.31) ALDH1A1KDM4EGAAMEN1KMT2A
SCHEMBL17499711 0.78 KDM4E (0.35) ALDH1A1KDM4EHPGDHSD17B10NR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed