Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499373 | 1.00 | KDM4E (0.32) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL17499812 | 0.90 | KDM4E (0.34) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL17499816 | 0.90 | KDM4E (0.34) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL16097063 | 0.87 | KDM4E (0.38) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL16100612 | 0.87 | CYP1B1 (0.42) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL16097064 | 0.87 | KDM4E (0.38) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL16100614 | 0.87 | CYP1B1 (0.42) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL17499646 | 0.83 | KDM4E (0.31) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL17499548 | 0.82 | ALDH1A1 (0.32) | KDM4EMAPTHTTLMNAMEN1 | |
| SCHEMBL17499549 | 0.82 | ALDH1A1 (0.32) | KDM4EMAPTHTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |