Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499447 | 1.00 | ALDH1A1 (0.34) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499208 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499210 | 0.86 | ALDH1A1 (0.46) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499439 | 0.77 | KDM1A (0.34) | KMT2A | |
| SCHEMBL17499466 | 0.77 | KMT2A (0.30) | ALDH1A1KMT2AHDAC1HDAC2HPGD | |
| SCHEMBL17499463 | 0.77 | KMT2A (0.30) | ALDH1A1KMT2AHDAC1HDAC2HPGD | |
| SCHEMBL17499530 | 0.77 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499525 | 0.77 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 | |
| SCHEMBL17499505 | 0.76 | — | — | |
| SCHEMBL17499603 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4EHSD17B10CASP1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |