Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499487 | 1.00 | KDM4E (0.40) | KDM4EMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL5587760 | 0.87 | CTH (0.40) | KDM4EKMT2AGAARAB9ANPC1 | |
| SCHEMBL5587762 | 0.87 | CTH (0.40) | KDM4EKMT2AGAARAB9ANPC1 | |
| SCHEMBL16097295 | 0.87 | CTH (0.33) | KDM4EMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL16097296 | 0.87 | CTH (0.33) | KDM4EMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL17499104 | 0.86 | CTH (0.33) | KDM4EMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL5589552 | 0.86 | CTH (0.39) | KDM4EKMT2AGAARAB9ANPC1 | |
| SCHEMBL28040290 | 0.85 | KDM4E (0.33) | KDM4EMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL16097860 | 0.83 | NR4A1 (0.49) | KDM4EMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL16097858 | 0.83 | NR4A1 (0.49) | KDM4EMAPTL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |