Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499180 | 0.87 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL17499734 | 0.87 | NPSR1 (0.32) | NPC1 | |
| SCHEMBL17499158 | 0.86 | SYK (0.35) | MEN1KMT2ANPC1NSD2HSP90AA1 | |
| SCHEMBL17499668 | 0.85 | NPC1 (0.41) | MEN1KMT2ANPC1NSD2HSP90AA1 | |
| SCHEMBL16096106 | 0.85 | ALDH1A1 (0.33) | MEN1KMT2ANPC1HSP90AA1KDM4E | |
| SCHEMBL16097047 | 0.83 | KDM4E (0.36) | MEN1KMT2ANPC1HSP90AA1KDM4E | |
| SCHEMBL16097100 | 0.82 | CYP2C9 (0.34) | MEN1KMT2ANPC1NSD2HSP90AA1 | |
| SCHEMBL17499686 | 0.81 | — | — | |
| SCHEMBL17499156 | 0.81 | CYP19A1 (0.32) | ALDH1A1 | |
| SCHEMBL17499300 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |