Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16097018 | 0.87 | POLB (0.46) | POLBMEN1KMT2ALMNAGRIN1 | |
| SCHEMBL16097016 | 0.87 | POLB (0.46) | POLBMEN1KMT2ALMNAGRIN1 | |
| SCHEMBL17499801 | 0.85 | NR4A1 (0.41) | POLBMEN1KMT2ACTHLMNA | |
| SCHEMBL16097024 | 0.85 | POLB (0.34) | POLBMEN1KMT2ACTHCYP19A1 | |
| SCHEMBL16097026 | 0.85 | POLB (0.34) | POLBMEN1KMT2ACTHCYP19A1 | |
| SCHEMBL17499230 | 0.82 | SLC6A2 (0.33) | MEN1KMT2ANOTUMGRIN1GRIN2B | |
| SCHEMBL16096931 | 0.82 | GRIN1 (0.33) | MEN1KMT2AGRIN1GRIN2BALDH1A1 | |
| SCHEMBL17499341 | 0.81 | ALDH1A1 (0.44) | POLBMEN1KMT2ACYP11B2LMNA | |
| SCHEMBL16095579 | 0.80 | GRIN1 (0.33) | MEN1KMT2AHTR1ADRD2GRIN1 | |
| SCHEMBL17499781 | 0.80 | KDM4E (0.31) | MEN1KMT2AGRIN1GRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |