Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499408 | 0.86 | GAA (0.35) | SMN1; SMN2NPC1KDM4EMEN1USP2 | |
| SCHEMBL16096427 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2NPC1TP53PKMRAB9A | |
| SCHEMBL16096426 | 0.85 | ALDH1A1 (0.40) | SMN1; SMN2NPC1TP53PKMRAB9A | |
| SCHEMBL17499575 | 0.85 | — | — | |
| SCHEMBL17499318 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1TP53PKMRAB9A | |
| SCHEMBL17499315 | 0.83 | SMN1; SMN2 (0.35) | SMN1; SMN2NPC1TP53PKMRAB9A | |
| SCHEMBL17499263 | 0.80 | KDM4E (0.32) | SMN1; SMN2KDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL17499438 | 0.79 | NPSR1 (0.31) | SMN1; SMN2NPC1TP53PKMRAB9A | |
| SCHEMBL17499118 | 0.78 | MEN1 (0.39) | SMN1; SMN2NPC1PKMRAB9AKDM4E | |
| SCHEMBL17499722 | 0.78 | KDM4E (0.30) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |