SCHEMBL17499700

SCHEMBL17499700

CC(=NCc1ccccc1O[SiH](C)C)c1ncc(C)cn1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIN1 Q05586 3/20 0.33
GRIN2B Q13224 3/20 0.33
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17499814 0.85 GRIN2B (0.44) GRIN1GRIN2B
SCHEMBL17499612 0.85 GRIN1 (0.32) GRIN1GRIN2BHTR7
SCHEMBL17499665 0.83 GRIN2B (0.33) GRIN1GRIN2BHTR7
SCHEMBL17499101 0.80 POLB (0.36) GRIN1GRIN2BHTR7
SCHEMBL17499645 0.77 ALDH1A1 (0.32)
SCHEMBL17499694 0.77 GRIN2B (0.33) GRIN1GRIN2BHTR7
SCHEMBL17499662 0.76 GRIN1 (0.32) GRIN1GRIN2B
SCHEMBL16096615 0.76 GRIN1 (0.32) GRIN1GRIN2BHTR7
SCHEMBL16101946 0.76 GRIN1 (0.31) GRIN1GRIN2BHTR7
SCHEMBL17499432 0.76 NPC1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2969593-B1 POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES BRIDGESTONE CORP (JP) 2020-11-04 EP disclosed
US-9850328-B2 Polymers functionalized with heterocyclic imines BRIDGESTONE CORPORATION (JP) 2017-12-26 US disclosed
US-20160039958-A1 Polymers Functionalized With Heterocyclic Imines BRIDGESTONE CORPORATION (JP) 2016-02-11 US disclosed