Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499153 | 0.87 | SMN1; SMN2 (0.45) | POLBL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17499560 | 0.85 | GRIN1 (0.32) | MEN1KMT2AHTR7GRIN1GRIN2B | |
| SCHEMBL17499101 | 0.84 | POLB (0.36) | POLBL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17499665 | 0.80 | GRIN2B (0.33) | HTR7GRIN1GRIN2B | |
| SCHEMBL17499485 | 0.78 | KMT2A (0.36) | POLBL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL16096271 | 0.78 | GRIN1 (0.32) | HTR7GRIN1GRIN2B | |
| SCHEMBL16096272 | 0.78 | GRIN1 (0.32) | HTR7GRIN1GRIN2B | |
| SCHEMBL16098121 | 0.77 | GRIN2B (0.32) | HTR7GRIN1GRIN2B | |
| SCHEMBL28039894 | 0.75 | KDM4E (0.45) | POLBL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL17499240 | 0.74 | MEN1 (0.34) | POLBL3MBTL1SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |