Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28039894 | 0.87 | KDM4E (0.45) | SMN1; SMN2RXFP1L3MBTL1SLC6A2SLC6A4 | |
| SCHEMBL17499709 | 0.87 | POLB (0.37) | SMN1; SMN2RXFP1L3MBTL1GRIN2BGRIN1 | |
| SCHEMBL17499101 | 0.86 | POLB (0.36) | SMN1; SMN2RXFP1L3MBTL1GRIN2BGRIN1 | |
| SCHEMBL17499731 | 0.84 | GRIN2B (0.42) | SMN1; SMN2GRIN2BGRIN1MEN1KMT2A | |
| SCHEMBL17499814 | 0.78 | GRIN2B (0.44) | SMN1; SMN2GRIN2BGRIN1MEN1KMT2A | |
| SCHEMBL17499330 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2RXFP1L3MBTL1GRIN2BGRIN1 | |
| SCHEMBL16096599 | 0.76 | GRIN2B (0.42) | SMN1; SMN2L3MBTL1GRIN2BGRIN1CLK2 | |
| SCHEMBL16096597 | 0.76 | GRIN2B (0.42) | SMN1; SMN2L3MBTL1GRIN2BGRIN1CLK2 | |
| SCHEMBL16095180 | 0.76 | GRIN2B (0.44) | SMN1; SMN2L3MBTL1GRIN2BGRIN1CLK2 | |
| SCHEMBL16095182 | 0.76 | GRIN2B (0.44) | SMN1; SMN2L3MBTL1GRIN2BGRIN1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2969593-B1 | POLYMERS FUNCTIONALIZED WITH HETEROCYCLIC IMINES | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| CN-105209268-B | Heterocyclic imine functionalized polymers | 株式会社普利司通 | 2018-05-04 | — | — | CN | disclosed |
| US-9850328-B2 | Polymers functionalized with heterocyclic imines | BRIDGESTONE CORPORATION (JP) | 2017-12-26 | — | — | US | disclosed |
| US-20160039958-A1 | Polymers Functionalized With Heterocyclic Imines | BRIDGESTONE CORPORATION (JP) | 2016-02-11 | — | — | US | disclosed |
| CN-105209268-A | Heterocyclic imine functionalized polymers | BRIDGESTONE CORP | 2015-12-30 | — | — | CN | disclosed |