SCHEMBL17499861

SCHEMBL17499861

CC(=CCCC(=O)O)C(=O)O.[Hf]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 2/20 0.41
FNTA P49354 2/20 0.40
FNTB P49356 2/20 0.40
LMNA P02545 2/20 0.40
SLC15A2 Q16348 1/20 0.40
MAPT P10636 2/20 0.39
KDM4E B2RXH2 2/20 0.39
ATM Q13315 1/20 0.39
FFAR1 O14842 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP19A1 P11511 1/20 0.39
RXRA P19793 1/20 0.39
OXER1 Q8TDS5 1/20 0.39
BACE1 P56817 1/20 0.39
CD81 P60033 1/20 0.39
EGLN1 Q9GZT9 3/20 0.36
ALKBH5 Q6P6C2 1/20 0.36
SUCNR1 Q9BXA5 1/20 0.36
FFAR3 O14843 1/20 0.36
HDAC3 O15379 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL33626 0.98 LMNA (0.42) PPARGFNTAFNTBLMNASLC15A2
SCHEMBL435540 0.98 LMNA (0.42) PPARGFNTAFNTBLMNASLC15A2
SCHEMBL17499944 0.95 PPARG (0.41) PPARGFNTAFNTBLMNASLC15A2
SCHEMBL3959910 0.84 LMNA (0.37) PPARGFNTAFNTBLMNASLC15A2
SCHEMBL431917 0.84 PPARG (0.44) PPARGFNTAFNTBLMNAMAPT
SCHEMBL431915 0.84 PPARG (0.44) PPARGFNTAFNTBLMNAMAPT
SCHEMBL2918368 0.83 KDM4E (0.45) PPARGFNTAFNTBLMNASLC15A2
SCHEMBL2918372 0.83 KDM4E (0.45) PPARGFNTAFNTBLMNASLC15A2
SCHEMBL699959 0.82 PPARG (0.48) PPARGLMNAMAPTATMFFAR1
Succinic Acid SCHEMBL17363357 0.82 LMNA (0.42) PPARGFNTAFNTBLMNASLC15A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160045402-A1 INFILTRATION SOLUTION FOR TREATING AN ENAMEL LESION ERNST MUEHLBAUER GMBH & CO. KG (DE) 2016-02-18 US disclosed