Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | RORA | P35398 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17499983 | 0.79 | TSHR (0.41) | TSHRPOLBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL17499995 | 0.78 | KCNA3 (0.48) | DRD2DRD3 | |
| SCHEMBL17499988 | 0.75 | KCNH2 (0.59) | — | |
| SCHEMBL17500004 | 0.73 | KCNH2 (0.57) | — | |
| SCHEMBL707467 | 0.69 | PLD1 (0.41) | HTR1ADRD2HTR2A | |
| SCHEMBL708145 | 0.67 | CA12 (0.41) | DRD2HTR2ADRD3 | |
| SCHEMBL19106957 | 0.66 | KCNH2 (0.41) | TSHRALDH1A1KDM4EHSD17B10 | |
| SCHEMBL27711964 | 0.66 | TRPV1 (0.37) | HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL11999881 | 0.65 | HTR3E (0.51) | GAAALDH1A1SMN1; SMN2KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL2797522 | 0.65 | HTR3E (0.50) | GAAALDH1A1SMN1; SMN2KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016024096-A1 | ANTIBACTERIAL COMPOUNDS | REDX PHARMA PLC (GB) | 2016-02-18 | — | — | WO | disclosed |