⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139865 | 0.97 | — | — | |
| SCHEMBL3240865 | 0.71 | — | — | |
| Sulfurous Acid SCHEMBL27897276 | 0.69 | — | — | |
| SCHEMBL23829641 | 0.67 | — | — | |
| SCHEMBL5794937 | 0.67 | — | — | |
| SCHEMBL10776738 | 0.67 | MEN1 (0.33) | — | |
| Sulfurous Acid SCHEMBL25287274 | 0.67 | — | — | |
| SCHEMBL10012479 | 0.67 | — | — | |
| SCHEMBL25453246 | 0.65 | — | — | |
| Allylamine SCHEMBL7866713 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511166-A | A kind of synthetic method of two arylmethyls alkyl sulfone | UNIV CHENGDU TECHNOLOGY | 2019-11-29 | — | — | CN | claimed |
| CN-106631926-B | A kind of method of selectivity synthesis aryl methyl sulfone and beta-hydroxylic sulfone derivation | 华南理工大学 | 2018-12-14 | — | — | CN | claimed |
| CN-106631926-A | Method for selectively compounding aryl methyl sulphone and belta-hydroxy sulphone derivative | 华南理工大学 | 2017-05-10 | — | — | CN | claimed |
| US-11529356-B2 | 2-(morpholin-4-yl)-1,7-naphthyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-12-20 | — | — | US | disclosed |
| CN-110204544-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110256427-B | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-108699057-B | 5-substituted 2- (morpholin-4-yl) -1, 7-naphthyridines | 拜耳医药股份公司 | 2021-11-09 | — | — | CN | disclosed |
| EP-3395818-B1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | Bayer Pharma AG (DE) | 2021-09-22 | — | — | EP | disclosed |
| US-20200383991-A1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-12-10 | — | — | US | disclosed |
| US-10772893-B2 | 2-(morpholin-4-yl)-1,7-naphthyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-09-15 | — | — | US | disclosed |
| US-10729680-B2 | 5-substituted 2-(morpholin-4-yl)-1,7-naphthyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2020-08-04 | — | — | US | disclosed |
| WO-2017121684-A1 | 5-SUBSTITUTED 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-07-20 | — | — | WO | disclosed |
| EP-3177619-A1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | Bayer Pharma Aktiengesellschaft (DE) | 2017-06-14 | — | — | EP | disclosed |
| CN-106795156-A | 2- (morpholin-4-yl) -1, 7-naphthyridine | 拜耳制药股份公司 | 2017-05-31 | — | — | CN | disclosed |
| CN-106631926-A | Method for selectively compounding aryl methyl sulphone and belta-hydroxy sulphone derivative | 华南理工大学 | 2017-05-10 | — | — | CN | disclosed |
| US-9549932-B2 | 2-(morpholin-4-yl)-1,7-naphthyridines | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-01-24 | — | — | US | disclosed |
| US-20160287604-A1 | 2-(MORPHOLIN-4-YL)-1,7-NAPHTHYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-10-06 | — | — | US | disclosed |
| CN-105829285-A | Quinazolinone and isoquinolinone derivatives | 中外制药株式会社 | 2016-08-03 | — | — | CN | disclosed |
| WO-2016020320-A1 | 2-(MORPHOLIN-4-YL)-L,7-NAPHTHYRIDINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-02-11 | — | — | WO | disclosed |
| CN-104114614-A | COLD-BOX BINDING AGENT SYSTEMS AND MIXTURES FOR USE AS ADDITIVES FOR SUCH BINDING AGENT SYSTEMS | HUETTENES ALBERTUS | 2014-10-22 | — | — | CN | disclosed |